Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002192 | 0.85 | RIPK1 (0.41) | MEN1KMT2ASMN1; SMN2KDM4EGPR119 | |
| SCHEMBL20757256 | 0.82 | KDM4E (0.48) | NR3C2SMN1; SMN2KDM4EGPR119TP53 | |
| SCHEMBL21527897 | 0.80 | MEN1 (0.49) | MEN1KMT2AKDM4EMAPTTHRB | |
| SCHEMBL20002692 | 0.80 | MEN1 (0.49) | MEN1KMT2AKDM4EMAPTTHRB | |
| SCHEMBL19995889 | 0.80 | MEN1 (0.49) | MEN1KMT2AKDM4EMAPTTHRB | |
| SCHEMBL8221143 | 0.79 | MEN1 (0.48) | MEN1KMT2AKDM4EMAPTTHRB | |
| SCHEMBL19404908 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EGPR119TP53MAPT | |
| SCHEMBL20438978 | 0.78 | SMN1; SMN2 (0.59) | MEN1KMT2ASMN1; SMN2KDM4EGPR119 | |
| SCHEMBL21527851 | 0.78 | MEN1 (0.44) | MEN1KMT2AKDM4EGPR119MAPT | |
| SCHEMBL21527850 | 0.78 | MEN1 (0.44) | MEN1KMT2AKDM4EGPR119MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014012563-A1 | COMPOUNDS FOR ENHANCING THE COGNITIVE FUNCTION | UCB PHARMA, S.A. (BE) | 2014-01-23 | — | — | WO | disclosed |