⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398246 | 0.75 | — | — | |
| SCHEMBL9304046 | 0.74 | TSHR (0.37) | — | |
| SCHEMBL15941441 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL1554134 | 0.74 | CYP2D6 (0.30) | — | |
| SCHEMBL9421349 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL10752559 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL23928459 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL5486101 | 0.72 | — | — | |
| SCHEMBL17049378 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL9421345 | 0.71 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9322960-B2 | Method of making a contact lens | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2016-04-26 | — | — | US | claimed |
| US-20150247956-A1 | METHOD OF MAKING A CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2015-09-03 | — | — | US | claimed |
| US-9322960-B2 | Method of making a contact lens | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2016-04-26 | — | — | US | disclosed |
| EP-2488895-B1 | METHOD OF MAKING A CONTACT LENS | SAUFLON CL LTD (GB) | 2015-11-25 | — | — | EP | disclosed |
| US-20150247956-A1 | METHOD OF MAKING A CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2015-09-03 | — | — | US | disclosed |
| US-9057821-B2 | Method of making a contact lens | SAUFLON CL LIMITED (GB) | 2015-06-16 | — | — | US | disclosed |
| US-20140171544-A1 | CONTACT LENS | SAUFLON CL LIMITED (GB) | 2014-06-19 | — | — | US | disclosed |
| US-8703891-B2 | Contact lens | SAUFLON CL LIMITED (GB) | 2014-04-22 | — | — | US | disclosed |
| US-20130015595-A1 | CONTACT LENS | SAUFLON CL LIMITED (GB) | 2013-01-17 | — | — | US | disclosed |
| EP-2488895-A1 | METHOD OF MAKING A CONTACT LENS | Sauflon CL Limited (GB) | 2012-08-22 | — | — | EP | disclosed |
| US-20120184696-A1 | METHOD OF MAKING A CONTACT LENS | SAUFLON CL LIMITED (GB) | 2012-07-19 | — | — | US | disclosed |
| EP-2087384-B1 | CONTACT LENS | SAUFLON CL LTD (GB) | 2010-08-25 | — | — | EP | disclosed |
| US-20100048847-A1 | Contact Lens | SAUFLON CL LIMITED (GB) | 2010-02-25 | — | — | US | disclosed |
| EP-2087384-A2 | CONTACT LENS | Sauflon CL Limited (GB) | 2009-08-12 | — | — | EP | disclosed |
| EP-1236068-B1 | CONTACT LENS | NOVARTIS AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008061992-A2 | CONTACT LENS | SAUFLON CL LIMITED (GB) | 2008-05-29 | — | — | WO | disclosed |
| US-7201481-B2 | Interpolymerization product of a (a) hydrophilic monomer with (b) a tris(siloxy)silyl group- containing monomer, (c) a wide variety of hydrophobic monomers (both aliphatic and aromatic) and usually a (d) polyfluorinated monomer | NOVARTIS AG (CH) | 2007-04-10 | — | — | US | disclosed |
| US-20060012751-A1 | Contact lens | ALCON INC. (CH) | 2006-01-19 | — | — | US | disclosed |
| US-6649722-B2 | Interpolymerization product of a (a) hydrophilic monomer with (b) a tris(siloxy)silyl group- containing monomer, (c) a wide variety of hydrophobic monomers (both aliphatic and aromatic) and usually a (d) polyfluorinated monomer | NOVARTIS AG (CH) | 2003-11-18 | — | — | US | disclosed |
| US-20020107337-A1 | Contact lens | ALCON INC. (CH) | 2002-08-08 | — | — | US | disclosed |