SCHEMBL23928459

SCHEMBL23928459

C=C(C)C(=O)OC(F)CC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9304046 0.83 TSHR (0.37) TSHRALDH1A1
SCHEMBL15941441 0.83 TSHR (0.33) TSHRALDH1A1
SCHEMBL29468154 0.79 TSHR (0.31) TSHR
SCHEMBL30172858 0.79 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL8466740 0.77
SCHEMBL29530643 0.76 TSHR (0.39) TSHR
SCHEMBL2563105 0.74 ALDH1A1 (0.43) TSHRALDH1A1
SCHEMBL31738676 0.73
SCHEMBL1554950 0.73
SCHEMBL9301999 0.72 TSHR (0.39) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP disclosed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US disclosed