⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044279 | 0.78 | — | — | |
| SCHEMBL6966539 | 0.75 | — | — | |
| SCHEMBL14404683 | 0.70 | MLYCD (0.37) | — | |
| SCHEMBL2093871 | 0.70 | — | — | |
| SCHEMBL15948552 | 0.68 | CYP19A1 (0.30) | — | |
| SCHEMBL294774 | 0.67 | — | — | |
| SCHEMBL21200715 | 0.67 | — | — | |
| Fluoride SCHEMBL25376565 | 0.65 | — | — | |
| SCHEMBL23457292 | 0.65 | — | — | |
| SCHEMBL22211156 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633206-B2 | Pyrrolo[2,3-D]pyrimidine compounds | PFIZER INC. (US) | 2014-01-21 | — | — | US | claimed |
| EP-2488524-B1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | PFIZER (US) | 2013-07-03 | — | — | EP | claimed |
| EP-2488524-A1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | claimed |
| US-20110136765-A1 | Pyrrolo[2,3-D]Pyrimidine Compounds | PFIZER INC. (US) | 2011-06-09 | — | — | US | claimed |
| WO-2011045702-A1 | PYRROLO[2,3-D] PYRIMIDINE COMPOUNDS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | claimed |
| WO-2010131146-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131147-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131145-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2023247489-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2023-12-28 | — | — | WO | disclosed |
| US-8633206-B2 | Pyrrolo[2,3-D]pyrimidine compounds | PFIZER INC. (US) | 2014-01-21 | — | — | US | disclosed |
| EP-2488524-B1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | PFIZER (US) | 2013-07-03 | — | — | EP | disclosed |
| EP-2488524-A1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| US-20110136765-A1 | Pyrrolo[2,3-D]Pyrimidine Compounds | PFIZER INC. (US) | 2011-06-09 | — | — | US | disclosed |
| WO-2011045702-A1 | PYRROLO[2,3-D] PYRIMIDINE COMPOUNDS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| WO-2010131147-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010131145-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010131146-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |