Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2217499 | 0.86 | CCND3 (0.51) | SYKCD63 | |
| SCHEMBL15550736 | 0.83 | SYK (0.65) | SYKCD63 | |
| SCHEMBL15552175 | 0.82 | SYK (0.44) | SYKCD63 | |
| SCHEMBL15552184 | 0.81 | SYK (0.50) | SYKCD63 | |
| SCHEMBL15552183 | 0.81 | SYK (0.50) | SYKCD63 | |
| SCHEMBL15551432 | 0.80 | SYK (0.58) | SYKCD63 | |
| SCHEMBL15550431 | 0.80 | SYK (0.56) | SYKCD63 | |
| SCHEMBL15550428 | 0.80 | JAK3 (0.51) | — | |
| SCHEMBL14927017 | 0.79 | WNT3A (0.46) | SYK | |
| SCHEMBL15551508 | 0.77 | SYK (0.50) | SYKCD63 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013188856-A1 | IMIDAZOPYRAZINE SYK INHIBITORS | GILEAD CONNECTICUT, INC. (US) | 2013-12-19 | — | — | WO | disclosed |
| US-20090075986-A1 | Anti-inflammatory medicaments | DECIPHERA PHARMACEUTICALS, LLC | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075986-A1 | Anti-inflammatory medicaments | MIF, PTGES2, TNF | SYK 349/4885CD63 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.