Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2101949 | 0.92 | EPHX1 (0.42) | THRBEPHX1ALDH1A1LMNADNM1 | |
| SCHEMBL30710203 | 0.92 | THRB (0.48) | THRBEPHX1ALDH1A1DNM1 | |
| SCHEMBL2103885 | 0.92 | EPHX1 (0.42) | THRBEPHX1ALDH1A1LMNADNM1 | |
| SCHEMBL2101722 | 0.92 | EPHX1 (0.42) | THRBEPHX1ALDH1A1LMNADNM1 | |
| SCHEMBL2101710 | 0.92 | EPHX1 (0.42) | THRBEPHX1ALDH1A1LMNADNM1 | |
| SCHEMBL25086738 | 0.92 | EPHX1 (0.42) | THRBEPHX1ALDH1A1LMNADNM1 | |
| SCHEMBL2100134 | 0.92 | EPHX1 (0.42) | THRBEPHX1ALDH1A1LMNADNM1 | |
| SCHEMBL1472438 | 0.92 | THRB (0.48) | THRBEPHX1ALDH1A1DNM1 | |
| SCHEMBL21689831 | 0.92 | EPHX1 (0.42) | THRBEPHX1ALDH1A1LMNADNM1 | |
| SCHEMBL2101563 | 0.90 | EPHX1 (0.41) | THRBEPHX1ALDH1A1LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2875021-A1 | BETA AMINO ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | Saint Louis University (US) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014015054-A1 | BETA AMINO ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SAINT LOUIS UNIVERSITY (US) | 2014-01-23 | — | — | WO | disclosed |