⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1557164 | 0.75 | — | — | |
| SCHEMBL8054564 | 0.73 | — | — | |
| SCHEMBL3251204 | 0.71 | — | — | |
| SCHEMBL3250534 | 0.69 | — | — | |
| SCHEMBL11120513 | 0.69 | — | — | |
| SCHEMBL18828544 | 0.69 | — | — | |
| SCHEMBL27666683 | 0.67 | — | — | |
| SCHEMBL27903448 | 0.67 | — | — | |
| SCHEMBL7834164 | 0.67 | — | — | |
| Propylamine SCHEMBL10802446 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1918158-B | Compounds and compositions as protein kinase inhibitors | IRM LLC | 2011-03-02 | — | — | CN | claimed |
| WO-2008156816-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | claimed |
| CN-1918158-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2007-02-21 | — | — | CN | claimed |
| US-4863945-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | claimed |
| EP-0051187-B1 | CATIONIC STYRYL DYES, THEIR PREPARATION AND THEIR USE IN DYING BASIC DYEABLE NATURAL OR SYNTHETIC SUBSTRATES | BAYER AG (DE) | 1984-03-28 | — | — | EP | claimed |
| US-4422969-A | FOR DYEING PAPER | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | claimed |
| EP-0051187-A2 | Cationic styryl dyes, their preparation and their use in dying basic dyeable natural or synthetic substrates | BAYER AG (DE) | 1982-05-12 | — | — | EP | claimed |
| CN-105992764-A | Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy | 艾伯维德国有限责任两合公司 | 2016-10-05 | — | — | CN | disclosed |
| CN-105764895-A | Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy | 艾伯维德国有限责任两合公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-104011028-A | N-SUBSTITUTED AMINOBENZOCYCLOHEPTENE, AMINOTETRALINE, AMINOINDANE AND PHENALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBVIE DEUTSCHLAND | 2014-08-27 | — | — | CN | disclosed |
| CN-103889968-A | Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy | ABBOTT GMBH & AMP | 2014-06-25 | — | — | CN | disclosed |
| CN-102083797-B | Tetrahydroisoquinolines, pharmaceutical compositions containing them and their use in therapy | ABBOTT GMBH & CO KG | 2014-06-04 | — | — | CN | disclosed |
| CN-101784533-B | 4-benzylaminoquinolines, pharmaceutical compositions containing them, and their use in therapy | ABBOTT GMBH & CO KG | 2013-08-21 | — | — | CN | disclosed |
| EP-0200915-B1 | AMINOPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| US-4863945-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0280951-A1 | Amino-propanol derivatives, process for their preparation and medicines containing these compounds, as well as intermediates | Roche Diagnostics GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |
| EP-0051187-B1 | CATIONIC STYRYL DYES, THEIR PREPARATION AND THEIR USE IN DYING BASIC DYEABLE NATURAL OR SYNTHETIC SUBSTRATES | BAYER AG (DE) | 1984-03-28 | — | — | EP | disclosed |
| US-4422969-A | FOR DYEING PAPER | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |