⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1556331 | 0.73 | — | — | |
| SCHEMBL7834164 | 0.67 | — | — | |
| SCHEMBL129372 | 0.64 | — | — | |
| SCHEMBL2282812 | 0.63 | — | — | |
| SCHEMBL17668147 | 0.60 | — | — | |
| SCHEMBL31332234 | 0.60 | — | — | |
| SCHEMBL3007652 | 0.60 | — | — | |
| SCHEMBL73703 | 0.60 | — | — | |
| SCHEMBL81843 | 0.57 | — | — | |
| Ammonia Solution, Strong SCHEMBL23326264 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837842-A | Novel bi-ring phenyl-pyridines/pyrazines for treatment of cancer | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | claimed |
| CN-104837842-A | Novel bi-ring phenyl-pyridines/pyrazines for treatment of cancer | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | disclosed |
| CN-100513398-C | 2- (2-hydroxybiphenyl-3-yl) -1H-benzimidazole-5-carboxamidine derivatives as factor VIIA inhibitors | AXYS PHARM INC (US) | 2009-07-15 | — | — | CN | disclosed |
| CN-1745070-A | 2- (2-hydroxybiphenyl-3-yl) -1H-benzimidazole-5-carboxamidine derivatives as factor VIIA inhibitors | AXYS PHARM INC (US) | 2006-03-08 | — | — | CN | disclosed |
| EP-0669336-B1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5663162-A | BACTERICIDES AND ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0669336-A1 | NOVEL CEPHEM DERIVATIVE | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-08-30 | — | — | EP | disclosed |