Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700692 | 0.81 | PIM1 (0.31) | — | |
| SCHEMBL1700694 | 0.81 | PIM1 (0.31) | — | |
| SCHEMBL1700691 | 0.81 | PIM1 (0.31) | — | |
| SCHEMBL10064043 | 0.75 | CARM1 (0.33) | CARM1PRMT1 | |
| SCHEMBL10897256 | 0.74 | APLNR (0.30) | APLNR | |
| SCHEMBL9156224 | 0.74 | APLNR (0.36) | APLNR | |
| SCHEMBL2931908 | 0.73 | APLNR (0.32) | APLNR | |
| SCHEMBL7875657 | 0.72 | — | — | |
| SCHEMBL16886414 | 0.71 | POLB (0.33) | APLNR | |
| SCHEMBL16224739 | 0.71 | APLNR (0.31) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882718-A1 | PYRAZOLE CARBOXAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F.HOFFMANN-LA ROCHE AG (CH) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014023258-A1 | PYRAZOLE CARBOXAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F.HOFFMANN-LA ROCHE AG (CH) | 2014-02-13 | — | — | WO | disclosed |