Bromide

Bromide

SCHEMBL15564400

Br.CCCCCCCCCCCCCCCCCC(C)(C)NCCC[Si](OC)(OC)OC

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
EPHX1 P07099 2/20 0.33
KDM4E B2RXH2 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
ACAT1 P24752 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL16931586 1.00 LMNA (0.44) LMNAEPHX1KDM4ETP53CYP3A4
SCHEMBL27124590 0.98 LMNA (0.45) LMNAEPHX1KDM4ETP53CYP3A4
SCHEMBL1123152 0.98 LMNA (0.45) LMNAEPHX1KDM4ETP53CYP3A4
SCHEMBL2135346 0.98 LMNA (0.45) LMNAEPHX1KDM4ETP53CYP3A4
SCHEMBL1123281 0.98 LMNA (0.45) LMNAEPHX1KDM4ETP53CYP3A4
Hydrochloric Acid SCHEMBL6559392 0.97 LMNA (0.44) LMNAEPHX1KDM4ETP53CYP3A4
Hydrochloric Acid SCHEMBL2747780 0.97 LMNA (0.44) LMNAEPHX1KDM4ETP53CYP3A4
Hydrochloric Acid SCHEMBL895838 0.97 LMNA (0.44) LMNAEPHX1KDM4ETP53CYP3A4
SCHEMBL1123424 0.90 LMNA (0.39) LMNA
Hydrochloric Acid SCHEMBL352060 0.85 LMNA (0.41) LMNAEPHX1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024114479-A1 NANO ANTIBACTERIAL MATERIAL AND ANTICOAGULANT COMPONENT COMPOSITION AND PLASMA PREPARATION METHOD THEREFOR 中国科学院深圳先进技术研究院 2024-06-06 WO claimed
WO-2024114479-A1 NANO ANTIBACTERIAL MATERIAL AND ANTICOAGULANT COMPONENT COMPOSITION AND PLASMA PREPARATION METHOD THEREFOR 中国科学院深圳先进技术研究院 2024-06-06 WO disclosed
EP-2880102-B1 PARTICULATE METAL OXIDE PARTICLES COMPRISING A METAL OXIDE CORE AND A COATING LAYER COMPRISING AN INORGANIC MATERIAL, A SILANE COUPLING AGENT AND/OR A HYDROPHOBIZING AGENT. CRODA INT PLC (GB) 2022-06-29 EP disclosed
US-10869826-B2 Particulate metal oxide particles comprising a metal oxide core and a coating layer comprising an inorganic material, a silane coupling agent and/or a hydrophobizing agent CRODA INTERNATIONAL PLC 2020-12-22 US disclosed
US-20150209260-A1 PARTICULATE METAL OXIDE PARTICLES COMPRISING A METAL OXIDE CORE AND A COATING LAYER COMPRISING AN INORGANIC MATERIAL, A SILANE COUPLING AGENT AND/OR A HYDROPHOBIZING AGENT CRODA INTERNATIONAL PLC (GB) 2015-07-30 US disclosed
EP-2880102-A1 PARTICULATE METAL OXIDE PARTICLES COMPRISING A METAL OXIDE CORE AND A COATING LAYER COMPRISING AN INORGANIC MATERIAL, A SILANE COUPLING AGENT AND/OR A HYDROPHOBIZING AGENT Croda International PLC (GB) 2015-06-10 EP disclosed
WO-2014023932-A1 PARTICULATE METAL OXIDE PARTICLES COMPRISING A METAL OXIDE CORE AND A COATING LAYER COMPRISING AN INORGANIC MATERIAL, A SILANE COUPLING AGENT AND/OR A HYDROPHOBIZING AGENT CRODA INTERNATIONAL PLC (GB) 2014-02-13 WO disclosed