Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 10/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16860097 | 1.00 | ENPP2 (0.47) | ENPP2S1PR5LPAR1S1PR1S1PR3 | |
| SCHEMBL15564413 | 1.00 | ENPP2 (0.47) | ENPP2S1PR5LPAR1S1PR1S1PR3 | |
| SCHEMBL15565252 | 0.93 | ENPP2 (0.44) | ENPP2S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL16860094 | 0.93 | ENPP2 (0.44) | ENPP2S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL16860095 | 0.93 | ENPP2 (0.44) | ENPP2S1PR5S1PR1S1PR3S1PR4 | |
| SCHEMBL15565778 | 0.89 | ENPP2 (0.42) | ENPP2S1PR5LPAR1FFAR1ALDH1A1 | |
| SCHEMBL16860090 | 0.89 | ENPP2 (0.42) | ENPP2S1PR5LPAR1FFAR1ALDH1A1 | |
| SCHEMBL15565780 | 0.89 | ENPP2 (0.42) | ENPP2S1PR5LPAR1FFAR1ALDH1A1 | |
| SCHEMBL16860089 | 0.88 | ENPP2 (0.49) | ENPP2S1PR5LPAR1FFAR1LTA4H | |
| SCHEMBL15565749 | 0.88 | ENPP2 (0.49) | ENPP2S1PR5LPAR1FFAR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2879673-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | Biogen Idec MA Inc. (US) | 2015-06-10 | — | — | EP | claimed |
| WO-2014025709-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-02-13 | — | — | WO | claimed |
| EP-2879673-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | Biogen Idec MA Inc. (US) | 2015-06-10 | — | — | EP | disclosed |
| WO-2014025709-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-02-13 | — | — | WO | disclosed |