Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 9/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15600013 | 1.00 | ENPP2 (0.43) | ENPP2L3MBTL1KMT2AMCHR1S1PR5 | |
| SCHEMBL16860073 | 1.00 | ENPP2 (0.43) | ENPP2L3MBTL1KMT2AMCHR1S1PR5 | |
| SCHEMBL16860083 | 0.94 | ENPP2 (0.46) | ENPP2L3MBTL1KMT2AMCHR1S1PR5 | |
| SCHEMBL15564847 | 0.94 | ENPP2 (0.46) | ENPP2L3MBTL1KMT2AMCHR1S1PR5 | |
| SCHEMBL15564849 | 0.94 | ENPP2 (0.46) | ENPP2L3MBTL1KMT2AMCHR1S1PR5 | |
| SCHEMBL15565128 | 0.92 | ENPP2 (0.46) | ENPP2L3MBTL1S1PR5ALDH1A1LMNA | |
| SCHEMBL16860077 | 0.92 | ENPP2 (0.46) | ENPP2L3MBTL1S1PR5ALDH1A1LMNA | |
| SCHEMBL15600008 | 0.92 | ENPP2 (0.46) | ENPP2L3MBTL1S1PR5ALDH1A1LMNA | |
| SCHEMBL16860089 | 0.84 | ENPP2 (0.49) | ENPP2L3MBTL1KMT2AS1PR5ALDH1A1 | |
| SCHEMBL15565749 | 0.84 | ENPP2 (0.49) | ENPP2L3MBTL1KMT2AS1PR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2879673-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | Biogen Idec MA Inc. (US) | 2015-06-10 | — | — | EP | disclosed |
| WO-2014025709-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-02-13 | — | — | WO | disclosed |