Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18920447 | 0.86 | ACP3 (0.47) | ACP3AOC3OPRM1PARP1ALDH1A1 | |
| SCHEMBL18946106 | 0.86 | ACP3 (0.47) | ACP3AOC3OPRM1PARP1ALDH1A1 | |
| SCHEMBL847191 | 0.86 | ACP3 (0.47) | ACP3AOC3OPRM1PARP1ALDH1A1 | |
| SCHEMBL888839 | 0.83 | ACP3 (0.41) | ACP3LMNAAOC3OPRM1PARP1 | |
| SCHEMBL10120515 | 0.81 | ACP3 (0.41) | ACP3LMNAHSD17B10AOC3OPRM1 | |
| SCHEMBL890215 | 0.81 | ALDH1A1 (0.47) | ACP3AOC3OPRM1ALDH1A1GAA | |
| SCHEMBL890129 | 0.81 | HDAC4 (0.47) | AOC3OPRM1 | |
| Hydrochloric Acid SCHEMBL7486109 | 0.79 | HDAC4 (0.46) | AOC3OPRM1 | |
| Hydrochloric Acid SCHEMBL7256377 | 0.79 | ALDH1A1 (0.46) | ACP3AOC3OPRM1ALDH1A1GAA | |
| SCHEMBL8921482 | 0.79 | ALDH1A1 (0.50) | LMNAALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968249-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | Samumed, LLC (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2882718-A1 | PYRAZOLE CARBOXAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F.HOFFMANN-LA ROCHE AG (CH) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014130869-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | SAMUMED, LLC (US) | 2014-08-28 | — | — | WO | disclosed |
| WO-2014023258-A1 | PYRAZOLE CARBOXAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F.HOFFMANN-LA ROCHE AG (CH) | 2014-02-13 | — | — | WO | disclosed |