SCHEMBL1556595

SCHEMBL1556595

CC/C(C(=O)O)=C(/C)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.39
FNTB P49356 2/20 0.39
THRB P10828 1/20 0.39
PGGT1B P53609 1/20 0.39
LDHA P00338 1/20 0.38
LDHB P07195 1/20 0.38
GRIK1 P39086 2/20 0.38
GRIA4 P48058 1/20 0.38
GRIK3 Q13003 1/20 0.38
GRIK5 Q16478 1/20 0.38
TDP1 Q9NUW8 3/20 0.36
FFAR3 O14843 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL554290 0.81 FNTA (0.54) FNTAFNTBTHRBPGGT1BGRIK1
SCHEMBL164727 0.81 FNTA (0.54) FNTAFNTBTHRBPGGT1BGRIK1
SCHEMBL554287 0.81 FNTA (0.54) FNTAFNTBTHRBPGGT1BGRIK1
SCHEMBL1557479 0.81 FNTA (0.50) FNTAFNTBTHRBPGGT1BLDHA
SCHEMBL8852386 0.80 FNTA (0.43) FNTAFNTBTHRBPGGT1BLDHA
SCHEMBL304615 0.79 FNTA (0.52) FNTAFNTBTHRBPGGT1BGRIK1
SCHEMBL5404918 0.79 LDHA (0.42) FNTAFNTBTHRBPGGT1BLDHA
SCHEMBL268870 0.79
SCHEMBL5404916 0.79 LDHA (0.42) FNTAFNTBTHRBPGGT1BLDHA
SCHEMBL304617 0.79 FNTA (0.52) FNTAFNTBTHRBPGGT1BGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10166527-B2 Surface modification of porous base supports MERCK PATENT GMBH (DE) 2019-01-01 US claimed
EP-2310104-B1 MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-10-18 EP claimed
EP-2152405-B2 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-04-05 EP claimed
US-20150298097-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS MERCK PATENT GMBH (DE) 2015-10-22 US claimed
EP-2914377-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS Merck Patent GmbH (DE) 2015-09-09 EP claimed
WO-2014067605-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS MERCK PATENT GMBH (DE) 2014-05-08 WO claimed
US-8673988-B2 Graft copolymers for ion exchange chromatography MERCK PATENT GMBH (DE) 2014-03-18 US claimed
EP-2152405-B1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2012-10-17 EP claimed
JP-2011529508-A 2011-12-08 JP claimed
US-20110136925-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-06-09 US claimed
EP-2310104-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY Merck Patent GmbH (DE) 2011-04-20 EP claimed
WO-2010012358-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2010-02-04 WO claimed
JP-6116287-A None JP disclosed
JP-5097699-A None JP disclosed
US-11446356-B2 Peptides and related compositions and methods THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-09-20 US disclosed
US-20220098233-A1 Mixed Bed Ion Exchange Adsorber EMD MILLIPORE CORP (US) 2022-03-31 US disclosed
JP-H06116287-A PROPENAMIDE DERIVATIVE, ITS POLYMER AND ITS USE FUJI PHOTO FILM CO LTD 1994-04-26 JP disclosed
JP-H0597699-A CANCER METASTASIS INHIBITOR COMPOSED OF PROPENAMIDE DERIVATIVE POLYMER FUJI PHOTO FILM CO LTD 1993-04-20 JP disclosed
EP-0503301-A2 Peptide derivatives and application thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-09-16 EP disclosed
JP-H00597699-A 0001-01-01 JP disclosed