Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15567318 | 0.86 | RORC (1.00) | RORC | |
| SCHEMBL15568392 | 0.85 | RORC (1.00) | RORCPPARG | |
| SCHEMBL15567534 | 0.85 | RORC (1.00) | RORCPPARG | |
| SCHEMBL15570140 | 0.84 | RORC (1.00) | RORCPPARG | |
| SCHEMBL15568789 | 0.84 | RORC (1.00) | RORCPPARG | |
| SCHEMBL15570138 | 0.84 | RORC (0.72) | RORCPPARG | |
| SCHEMBL12683711 | 0.82 | RORC (0.64) | RORCPPARG | |
| SCHEMBL15570546 | 0.82 | RORC (0.71) | RORCPPARG | |
| SCHEMBL16968523 | 0.81 | RORC (1.00) | RORC | |
| SCHEMBL15567701 | 0.81 | RORC (1.00) | RORCPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920149-B1 | 3-AMINOCYCLOALKYL COMPOUNDS AS ROR-GAMMA-T INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME (US) | 2019-03-20 | — | — | EP | claimed |
| WO-2014026330-A1 | 3-AMINOCYCLOALKYL COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2014-02-20 | — | — | WO | claimed |
| EP-2920149-A2 | 3-AMINOCYCLOALKYL COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF | Merck Sharp & Dohme Corp. (US) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014026330-A1 | 3-AMINOCYCLOALKYL COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2014-02-20 | — | — | WO | disclosed |
| WO-2014028600-A2 | 3-AMINOCYCLOALKYL COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2014-02-20 | — | — | WO | disclosed |