Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875445 | 0.97 | CHRNB4 (0.42) | ALDH1A1KMT2AMCOLN3CHRNB4CHRNA3 | |
| SCHEMBL28875444 | 0.97 | CHRNB4 (0.42) | ALDH1A1KMT2AMCOLN3CHRNB4CHRNA3 | |
| SCHEMBL22106451 | 0.86 | CHRNB4 (0.54) | CHRNB4CHRNA3 | |
| SCHEMBL15607421 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KMT2AMCOLN3CHRNB4CHRNA3 | |
| SCHEMBL5240331 | 0.83 | CHRNB4 (0.57) | CHRNB4CHRNA3 | |
| SCHEMBL6205627 | 0.83 | CHRNB4 (0.57) | CHRNB4CHRNA3 | |
| SCHEMBL15607334 | 0.83 | F2RL3 (0.42) | ALDH1A1KMT2AMCOLN3MEN1CYP2C19 | |
| SCHEMBL15566739 | 0.83 | F2RL3 (0.42) | ALDH1A1KMT2AMCOLN3MEN1CYP2C19 | |
| SCHEMBL15566901 | 0.83 | F2RL3 (0.42) | ALDH1A1KMT2AMCOLN3MEN1CYP2C19 | |
| SCHEMBL19052294 | 0.82 | KMT2A (0.37) | ALDH1A1KMT2AMCOLN3CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2880031-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2015-06-10 | — | — | EP | disclosed |
| WO-2014025706-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-02-13 | — | — | WO | disclosed |