Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | DRD1 | P21728 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | DRD5 | P21918 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.37 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.37 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.37 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.37 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.37 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17135722 | 0.96 | OPRM1 (0.44) | TAAR1OPRM1SLC18A3SIGMAR1KDM1A | |
| SCHEMBL15571072 | 0.89 | TAAR1 (0.39) | TAAR1OPRM1SLC18A3SIGMAR1KDM1A | |
| SCHEMBL16221385 | 0.79 | KDM1A (0.46) | TAAR1OPRM1SLC18A3SIGMAR1KDM1A | |
| SCHEMBL32672366 | 0.79 | KDM1A (0.41) | TAAR1OPRM1SLC18A3SIGMAR1KDM1A | |
| SCHEMBL31478425 | 0.79 | POLB (0.40) | — | |
| SCHEMBL17712914 | 0.78 | OPRM1 (0.45) | OPRM1SLC18A3SIGMAR1KDM1AMAOB | |
| SCHEMBL17712743 | 0.78 | OPRM1 (0.45) | OPRM1SLC18A3SIGMAR1KDM1AMAOB | |
| SCHEMBL2303349 | 0.78 | CYP2D6 (0.38) | HPGDCYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL23466001 | 0.76 | HTR2A (0.44) | OPRM1SLC18A3SIGMAR1KDM1AMAOB | |
| SCHEMBL19629563 | 0.76 | HTR2A (0.44) | OPRM1SLC18A3SIGMAR1KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895471-A1 | PIPERIDINE AMIDE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | Bristol-Myers Squibb Company (US) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014025854-A1 | PIPERIDINE AMIDE DERIVATIVES AS HIV ATTACHMENT INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-02-13 | — | — | WO | disclosed |