Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15569514 | 0.78 | ATM (0.38) | ALDH1A1KDM4EL3MBTL1PKMMAPK1 | |
| SCHEMBL15568782 | 0.74 | KDM4E (0.43) | ALDH1A1KDM4EL3MBTL1HSD17B10HPGD | |
| SCHEMBL15569610 | 0.73 | ATM (0.37) | ALDH1A1KDM4EL3MBTL1PIK3CAMEN1 | |
| SCHEMBL6093597 | 0.72 | HTT (0.52) | ALDH1A1KDM4EL3MBTL1PIK3CAHSD17B10 | |
| SCHEMBL15569312 | 0.72 | KDM4E (0.41) | ALDH1A1KDM4EL3MBTL1HSD17B10HPGD | |
| SCHEMBL387677 | 0.71 | SMN1; SMN2 (0.42) | ALDH1A1KDM4EL3MBTL1HSD17B10HPGD | |
| SCHEMBL15570276 | 0.70 | KDM4E (0.41) | ALDH1A1KDM4EL3MBTL1HSD17B10HPGD | |
| SCHEMBL22900489 | 0.70 | KMT2A (0.46) | ALDH1A1KDM4EL3MBTL1HSD17B10USP2 | |
| SCHEMBL391742 | 0.70 | KDM5B (0.45) | ALDH1A1KDM4EL3MBTL1MAPK1TP53 | |
| SCHEMBL17473231 | 0.69 | PIK3CA (0.48) | ALDH1A1KDM4EL3MBTL1PIK3CAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014031971-A1 | HERBICIDAL PYRIDAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-27 | — | — | WO | disclosed |