Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15570041 | 0.87 | ALDH1A1 (0.39) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL15569660 | 0.87 | KDM5B (0.42) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL15569737 | 0.83 | POLB (0.34) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL15568782 | 0.80 | KDM4E (0.43) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL15569312 | 0.78 | KDM4E (0.41) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL387677 | 0.77 | SMN1; SMN2 (0.42) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL15569366 | 0.77 | MAPT (0.31) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL4700865 | 0.76 | ADORA3 (0.47) | KDM4ESMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL22900489 | 0.76 | KMT2A (0.46) | KDM4ESMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL391742 | 0.76 | KDM5B (0.45) | KDM4ESMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014031971-A1 | HERBICIDAL PYRIDAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-27 | — | — | WO | disclosed |