Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.33 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093535 | 0.84 | SLC1A5 (0.43) | PGK1GRIN2BTRPV4SLC1A5KMO | |
| SCHEMBL8462016 | 0.78 | NOTUM (0.44) | NOTUMPGK1PDE3AEPHX1GRIN2B | |
| SCHEMBL20309113 | 0.76 | NOTUM (0.43) | NOTUMPGK1PDE3AEPHX1GRIN2B | |
| SCHEMBL11910291 | 0.76 | MAPT (0.46) | NOTUMPGK1PDE3AEPHX1SLC1A5 | |
| SCHEMBL363418 | 0.76 | HSD17B10 (0.46) | NOTUMPGK1PDE3AEPHX1GRIN2B | |
| SCHEMBL1555931 | 0.76 | CYP3A4 (0.46) | NOTUMPGK1PDE3AEPHX1GRIN2B | |
| SCHEMBL31342467 | 0.76 | NOTUM (0.43) | NOTUMPGK1PDE3AEPHX1GRIN2B | |
| SCHEMBL3763568 | 0.76 | NOTUM (0.47) | NOTUMPGK1PDE3AEPHX1GRIN2B | |
| SCHEMBL10933173 | 0.76 | NOTUM (0.43) | NOTUMPDE3A | |
| SCHEMBL1416864 | 0.76 | NOTUM (0.43) | NOTUMPGK1PDE3AEPHX1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3619196-B1 | 2-{[2-(PHENYLOXYMETHYL)PYRIDIN-5-YL]OXY}-ETHANAMIN-DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES E.G. FOR CROP PROTECTION | BAYER CROPSCIENCE AG (DE) | 2022-03-30 | — | — | EP | disclosed |
| US-10456379-B2 | Imidazole-based antimicrobial agents | PROCOMCURE BIOTECH GMBH (AT) | 2019-10-29 | — | — | US | disclosed |
| US-20170334887-A1 | Imidazole-Based Antimicrobial Agents | PROCOMCURE BIOTECH GMBH (AT) | 2017-11-23 | — | — | US | disclosed |
| WO-2014028669-A1 | NOVEL COMPOUNDS FOR MODULATION OF ROR-GAMMA ACTIVITY | BIOGEN IDEC MA INC. (US) | 2014-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334887-A1 | Imidazole-Based Antimicrobial Agents | TLR5, NISCH, SLC11A2 | NOTUM 2202/4885PGK1 1815/4885PDE3A 1019/4885 |
| US-10456379-B2 | Imidazole-based antimicrobial agents | TLR5, NISCH, SLC11A2 | NOTUM 2202/4885PGK1 1815/4885PDE3A 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.