Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.37 |
| ▸ | CACNG8 | Q8WXS5 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459404 | 0.84 | SLC6A4 (0.35) | NOTUMPDE3AGPR3HTR2ASLC6A4 | |
| SCHEMBL8462060 | 0.83 | SLC1A5 (0.44) | GPR3PYGLP2RX7EPHX2GRIN2B | |
| SCHEMBL12566385 | 0.78 | EPHX2 (0.53) | GPR3EPHX2HRH4PDE2A | |
| SCHEMBL363418 | 0.78 | HSD17B10 (0.46) | NOTUMPDE3AGRIN2BPGK1EPHX1 | |
| SCHEMBL1555931 | 0.78 | CYP3A4 (0.46) | NOTUMPDE3AGRIN2BPGK1GRIA1 | |
| SCHEMBL11910291 | 0.78 | MAPT (0.46) | NOTUMPDE3AGPR3PGK1EPHX1 | |
| SCHEMBL20309113 | 0.78 | NOTUM (0.43) | NOTUMPDE3AGRIN2BPGK1GRIA1 | |
| SCHEMBL10933173 | 0.78 | NOTUM (0.43) | NOTUMPDE3AHTR2ASLC6A4KCNH2 | |
| SCHEMBL3763568 | 0.78 | NOTUM (0.47) | NOTUMPDE3AEPHX2GRIN2BPGK1 | |
| SCHEMBL31342467 | 0.78 | NOTUM (0.43) | NOTUMPDE3AGRIN2BPGK1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981789-A | CHLORODENITRATING AROMATIC COMPOUNDS USING LESS CHLORINATING AGENT AND LOWER TEMPERATURES, THEN RECYCLING THE PRODUCT MIXTURE TO INCREASE THE YIELD | OCCIDENTAL CHEMICAL CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| US-4704483-A | FLUORINATION WITH POTASSIUM FLUORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1987-11-03 | — | — | US | disclosed |
| US-4582948-A | VAPOR PHASE CHLORO-DENITRATION REACTION | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0159388-A2 | Preparation of nuclear chlorinated compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-10-30 | — | — | EP | disclosed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | disclosed |