SCHEMBL1556897

SCHEMBL1556897

Clc1cc(Cl)c2c(Cl)ccnc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 4/20 0.44
SOS2 Q07890 1/20 0.41
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PIK3R1 P27986 1/20 0.38
PIK3CA P42336 1/20 0.38
CYP1A2 P05177 1/20 0.37
CASP6 P55212 1/20 0.36
AURKA O14965 1/20 0.36
AURKB Q96GD4 1/20 0.36
CHKA P35790 1/20 0.36
CCR1 P32246 2/20 0.35
CCR5 P51681 1/20 0.35
CCR8 P51685 1/20 0.35
AXL P30530 1/20 0.35
PRKCI P41743 1/20 0.35
PKM P14618 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30800065 1.00 NR4A2 (0.44) NR4A2SOS2MAPTKMT2ATDP1
SCHEMBL29872784 0.82 NR4A2 (0.41) NR4A2SOS2MAPTKMT2ATDP1
SCHEMBL7048479 0.82 NR4A2 (0.41) NR4A2SOS2MAPTKMT2ATDP1
SCHEMBL8057377 0.82 NR4A2 (0.41) NR4A2SOS2MAPTKMT2ATDP1
SCHEMBL7532122 0.80 NR4A2 (0.40) NR4A2SOS2MAPTKMT2ATDP1
SCHEMBL8069040 0.77 TDP1 (0.48) NR4A2SOS2MAPTKMT2ATDP1
SCHEMBL11891537 0.77 NR4A2 (0.38) NR4A2SOS2MAPTKMT2ATDP1
SCHEMBL11893004 0.77 NR4A2 (0.38) NR4A2SOS2MAPTKMT2ATDP1
SCHEMBL6465602 0.77 PARP1 (0.50) NR4A2MAPTKMT2AMEN1L3MBTL1
SCHEMBL29404834 0.77 PARP1 (0.50) NR4A2MAPTKMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108689927-B Phenoxyquinoline and synthesis method thereof 陕西恒润化学工业有限公司 2020-07-03 CN claimed
CN-109574923-A The preparation method of 4,5,7- trichloro-quinoline 浙江工业大学 2019-04-05 CN claimed
CN-108689927-A A kind of quinoxyfen and its synthetic method 陕西恒润化学工业有限公司 2018-10-23 CN claimed
CN-1119331-C Improved process for preparing halo-4-phenoxyquinolines DOW AGROSCIENCES LLC (US) 2003-08-27 CN claimed
EP-0960099-B1 IMPROVED PROCESS FOR THE PREPARATION OF HALO-4-PHENOXYQUINOLINES DOW AGROSCIENCES LLC (US) 2003-04-16 EP claimed
CN-1246112-A Improved process for preparation of halo-4-phenoxyquinolines DOW AGROSCIENCES LLC (US) 2000-03-01 CN claimed
EP-0960099-A1 IMPROVED PROCESS FOR THE PREPARATION OF HALO-4-PHENOXYQUINOLINES Dow AgroSciences LLC (US) 1999-12-01 EP claimed
US-5973153-A Process for the preparation of halo-4-phenoxyquinolines DOWELANCO LLC 1999-10-26 US claimed
WO-1998033774-A1 IMPROVED PROCESS FOR THE PREPARATION OF HALO-4-PHENOXYQUINOLINES DOW AGROSCIENCES LLC (US) 1998-08-06 WO claimed
CN-118325083-A Photosensitive polyamic acid ester resin, photosensitive polyamic acid ester resin glue solution, preparation method and application thereof 深圳先进电子材料国际创新研究院 2024-07-12 CN disclosed
CN-117801596-A Photosensitive polyimide resin composition and preparation method and application thereof 深圳先进电子材料国际创新研究院 2024-04-02 CN disclosed
CN-117756715-A Compound for preventing and treating plant diseases and application thereof 王昭策 2024-03-26 CN disclosed
CN-109232417-B Preparation method of 4-phenoxyl quinoline compound 浙江工业大学 2021-02-09 CN disclosed
CN-108689927-B Phenoxyquinoline and synthesis method thereof 陕西恒润化学工业有限公司 2020-07-03 CN disclosed
US-5245036-A Process for the preparation of 4-phenoxyquinoline compounds DOWELANCO (US) 1993-09-14 US disclosed
US-5240940-A Synergistic nmixture DOWELANCO (US) 1993-08-31 US disclosed
US-5202329-A Pyrimidinyloxy(thio)quinoline derivative, and agri-horticultural fungicide comprising the derivative as active ingredient MITSUI TOATSU CHEMICALS INC. (JP) 1993-04-13 US disclosed
US-5145843-A For plants DOWELANCO (US) 1992-09-08 US disclosed
EP-0497371-A1 Pyrimidinyloxy(thio)quinoline derivatives, preparation process of the derivative, and agri-horticultural fungicide comprising the derivative as active ingredient MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-08-05 EP disclosed
EP-0326330-A2 Quinoline, quinazoline, and cinnoline fungicides DowElanco (US) 1989-08-02 EP disclosed