Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ERN1 | O75460 | 3/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30800065 | 0.77 | NR4A2 (0.44) | TDP1CCR1CCR5CCR8MEN1 | |
| SCHEMBL1556897 | 0.77 | NR4A2 (0.44) | TDP1CCR1CCR5CCR8MEN1 | |
| SCHEMBL3709985 | 0.74 | NR4A2 (0.56) | TDP1CCR1CCR5CCR8MEN1 | |
| SCHEMBL8057377 | 0.73 | NR4A2 (0.41) | TDP1CCR1MEN1MAPTKMT2A | |
| SCHEMBL7048479 | 0.73 | NR4A2 (0.41) | TDP1MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL29872784 | 0.73 | NR4A2 (0.41) | TDP1MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL11893004 | 0.72 | NR4A2 (0.38) | TDP1MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL3252945 | 0.71 | NR4A2 (0.58) | TDP1ERN1CCR1CCR5CCR8 | |
| SCHEMBL7532122 | 0.71 | NR4A2 (0.40) | TDP1MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL1496336 | 0.71 | CCR1 (0.50) | TDP1ERN1CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117884-A | 4-substituted quinoline derivatives having fungicidal activity | DAEUBLE JOHN (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0925282-A1 | 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY | DOWELANCO (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998005645-A1 | 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 1998-02-12 | — | — | WO | disclosed |