Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568846 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20720005 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15569517 | 0.76 | CDK8 (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15569803 | 0.76 | POLB (0.35) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15568776 | 0.75 | MEN1 (0.33) | MEN1KMT2ALMNA | |
| SCHEMBL15569610 | 0.73 | ATM (0.37) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15570307 | 0.72 | TP53 (0.44) | SMN1; SMN2ALDH1A1MEN1KMT2ACDK8 | |
| SCHEMBL15569851 | 0.70 | TSHR (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15569697 | 0.70 | GAA (0.38) | SMN1; SMN2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL2779365 | 0.69 | MAPT (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014031971-A1 | HERBICIDAL PYRIDAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-27 | — | — | WO | claimed |
| WO-2014031971-A1 | HERBICIDAL PYRIDAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-27 | — | — | WO | disclosed |