Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15570064 | 0.88 | TP53 (0.43) | TP53LMNAMAPTSMN1; SMN2CDK8 | |
| SCHEMBL15570257 | 0.88 | TP53 (0.43) | TP53LMNAMAPTSMN1; SMN2CDK8 | |
| SCHEMBL15569628 | 0.85 | TP53 (0.41) | TP53LMNAMAPTSMN1; SMN2CDK8 | |
| SCHEMBL15569366 | 0.77 | MAPT (0.31) | LMNAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL15569851 | 0.77 | TSHR (0.51) | TP53LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL15569517 | 0.76 | CDK8 (0.51) | TP53LMNAMAPTSMN1; SMN2CDK8 | |
| SCHEMBL15569514 | 0.75 | ATM (0.38) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL15569784 | 0.74 | LMNA (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL15569408 | 0.72 | SMN1; SMN2 (0.40) | TP53LMNAMAPTSMN1; SMN2CDK8 | |
| SCHEMBL2781613 | 0.70 | RXFP1 (0.49) | TP53LMNAMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014031971-A1 | HERBICIDAL PYRIDAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-27 | — | — | WO | disclosed |