Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15569368 | 1.00 | RORC (0.69) | RORCPPARG | |
| SCHEMBL15571125 | 0.94 | RORC (0.68) | RORCPPARG | |
| SCHEMBL15569999 | 0.93 | RORC (0.66) | RORCPPARG | |
| SCHEMBL16875888 | 0.92 | RORC (0.65) | RORCPPARG | |
| SCHEMBL15570109 | 0.92 | RORC (0.59) | RORC | |
| SCHEMBL16875884 | 0.91 | RORC (0.64) | RORCPPARG | |
| SCHEMBL15571127 | 0.91 | RORC (0.66) | RORCPPARG | |
| SCHEMBL15570707 | 0.91 | RORC (0.63) | RORCPPARG | |
| SCHEMBL16875889 | 0.89 | RORC (0.62) | RORCPPARG | |
| SCHEMBL16884647 | 0.89 | RORC (0.58) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2884976-A2 | 3-CYCLOHEXENYL AND CYCLOHEXYL SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF | Merck Sharp & Dohme Corp. (US) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014028597-A2 | 3-CYCLOHEXENYL AND CYCLOHEXYL SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2014-02-20 | — | — | WO | disclosed |