Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15570774 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTMALT1MAPK1 | |
| SCHEMBL21361609 | 0.88 | MALT1 (0.47) | ALDH1A1KMT2AMAPTMALT1SYK | |
| SCHEMBL30135170 | 0.88 | MALT1 (0.47) | ALDH1A1KMT2AMAPTMALT1SYK | |
| SCHEMBL21359217 | 0.88 | MALT1 (0.47) | ALDH1A1KMT2AMAPTMALT1SYK | |
| SCHEMBL18085398 | 0.88 | MALT1 (0.47) | ALDH1A1KMT2AMAPTMALT1SYK | |
| SCHEMBL23102244 | 0.86 | SYK (0.46) | ALDH1A1KMT2AMAPTMALT1RAB9A | |
| SCHEMBL30500909 | 0.86 | SYK (0.52) | ALDH1A1MAPTMALT1SYKBRD4 | |
| SCHEMBL20777647 | 0.85 | MALT1 (0.45) | ALDH1A1KMT2AMALT1SYKBRD4 | |
| SCHEMBL20974125 | 0.84 | SYK (0.50) | ALDH1A1KMT2AMAPTMALT1SYK | |
| SCHEMBL24257237 | 0.84 | SYK (0.50) | ALDH1A1KMT2AMAPTMALT1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017185261-A1 | MOSAPRIDE ACTIVE METABOLITES, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF | 沈阳药科大学 | 2017-11-02 | — | — | WO | disclosed |
| WO-2014031872-A2 | SMALL MOLECULE INHIBITORS FOR TREATING PARASITIC INFECTIONS | THE BROAD INSTITUTE, INC. (US) | 2014-02-27 | — | — | WO | disclosed |