SCHEMBL15573077

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15574556	0.91	DDR2 (0.70)	DDR2RAF1CSF1RBRAFALDH1A1
	SCHEMBL16990693	0.90	HDAC1 (0.55)	DDR2RAF1HDAC1HDAC6HDAC11
	SCHEMBL15573192	0.89	DDR2 (0.54)	DDR2RAF1CSF1RPYGLPYGM
	SCHEMBL13603627	0.89	DDR2 (0.70)	DDR2RAF1CSF1RBRAFALDH1A1
	SCHEMBL13603632	0.88	DDR2 (0.72)	DDR2RAF1CSF1RBRAFALDH1A1
	SCHEMBL15574169	0.88	DDR2 (0.82)	DDR2RAF1CSF1RBRAFALDH1A1
	SCHEMBL17000011	0.88	DDR2 (0.69)	DDR2RAF1CSF1RBRAFALDH1A1
	SCHEMBL13603476	0.88	DDR2 (0.57)	DDR2RAF1CSF1RBRAFKDR
	SCHEMBL169207	0.87	DDR2 (0.59)	DDR2RAF1HDAC1HDAC6HDAC11
	SCHEMBL13603469	0.87	DDR2 (0.52)	DDR2RAF1BRAFKDRMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.