Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15575148 | 0.92 | GCKR (0.53) | GCKRGCK | |
| SCHEMBL15575336 | 0.91 | GCKR (0.54) | GCKRGCK | |
| SCHEMBL15575275 | 0.91 | GCKR (0.54) | GCKRGCK | |
| SCHEMBL15576170 | 0.90 | GCK (0.53) | GCKRGCK | |
| SCHEMBL15575586 | 0.88 | GCKR (0.55) | GCKRGCK | |
| SCHEMBL16932 | 0.87 | GCK (0.67) | GCKRGCK | |
| SCHEMBL18383 | 0.87 | GCK (0.67) | GCKRGCK | |
| SCHEMBL16675 | 0.87 | GCK (0.67) | GCKRGCK | |
| SCHEMBL17687 | 0.87 | GCK (0.66) | GCKRGCK | |
| SCHEMBL15575880 | 0.85 | GCK (0.48) | GCKRGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014035872-A1 | TRICYCLIC ALKYNES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN | AMGEN INC. (US) | 2014-03-06 | — | — | WO | disclosed |