SCHEMBL15575338

SCHEMBL15575338

N#Cc1cc2c3c(ccc4c5ccc6c7c(ccc(c1c34)c75)C(=O)NC6=O)C(=O)NC2=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.36
CHEK1 O14757 5/20 0.36
WEE1 P30291 4/20 0.36
PARP1 P09874 5/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MEN1 O00255 1/20 0.35
RGS12 O14924 1/20 0.35
USP2 O75604 1/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
CYP2C9 P11712 1/20 0.35
APEX1 P27695 1/20 0.35
CASP1 P29466 1/20 0.35
BRCA1 P38398 1/20 0.35
MTOR P42345 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1263254 0.97 PPOX (0.38) PPOXCHEK1WEE1PARP1NPSR1
SCHEMBL13923619 0.92 CHEK1 (0.38) PPOXCHEK1WEE1PARP1NPSR1
SCHEMBL12561990 0.88 NPSR1 (0.36) PPOXCHEK1WEE1PARP1NPSR1
SCHEMBL12562177 0.88 CHEK1 (0.33) PPOXCHEK1WEE1PARP1NPSR1
SCHEMBL12561977 0.87 CHEK1 (0.33) PPOXCHEK1WEE1PARP1NPSR1
SCHEMBL13606485 0.87 NPSR1 (0.35) PPOXCHEK1WEE1PARP1NPSR1
SCHEMBL13606484 0.85 NPSR1 (0.36) PPOXCHEK1WEE1PARP1NPSR1
SCHEMBL12894513 0.85 CHEK1 (0.32) PPOXCHEK1WEE1PARP1NPSR1
SCHEMBL13606709 0.85 CHEK1 (0.30) CHEK1WEE1
SCHEMBL12094144 0.84 CHEK1 (0.31) CHEK1WEE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2888768-A1 LIGHT-EMITTING TRANSISTORS WITH IMPROVED PERFORMANCE Polyera Corporation (US) 2015-07-01 EP disclosed
WO-2014035841-A1 NOVEL STRUCTURES FOR LIGHT-EMITTING TRANSISTORS POLYERA CORPORATION (US) 2014-03-06 WO disclosed
WO-2014035842-A1 LIGHT-EMITTING TRANSISTORS WITH IMPROVED PERFORMANCE POLYERA CORPORATION (US) 2014-03-06 WO disclosed