SCHEMBL155771

SCHEMBL155771

CC(O)COc1ccc(-c2ccccc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.78
KDM1A O60341 1/20 0.55
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.55
MAPT P10636 2/20 0.54
CHRNA7 P36544 2/20 0.53
CHRNB2 P17787 1/20 0.53
CHRNB4 P30926 1/20 0.53
CHRNA3 P32297 1/20 0.53
CHRNA4 P43681 1/20 0.53
PKM P14618 2/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ADRB2 P07550 1/20 0.49
ADRB1 P08588 1/20 0.49
CYP2D6 P10635 1/20 0.49
ADRB3 P13945 1/20 0.49
CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9513813 1.00 LMNA (0.78) LMNAKDM1AMAOAMAOBMAPT
SCHEMBL14840114 0.88 LMNA (0.66) LMNAKDM1AMAOAMAOBMAPT
SCHEMBL50453 0.88 LMNA (1.00) LMNAMAOACHRNA7CHRNB2CHRNB4
SCHEMBL3254859 0.88 LMNA (1.00) LMNAMAOACHRNA7CHRNB2CHRNB4
SCHEMBL2943775 0.88 LMNA (1.00) LMNAMAOACHRNA7CHRNB2CHRNB4
SCHEMBL1618880 0.88 LMNA (1.00) LMNAMAOACHRNA7CHRNB2CHRNB4
SCHEMBL5949941 0.85 LMNA (0.78) LMNAMAPTSMN1; SMN2ADRB2ADRB1
SCHEMBL4046461 0.85 LMNA (0.85) LMNAMAOASMN1; SMN2ADRB2ADRB1
SCHEMBL1496544 0.85 LMNA (0.85) LMNAMAOASMN1; SMN2ADRB2ADRB1
SCHEMBL9713476 0.85 LMNA (0.85) LMNAMAOASMN1; SMN2ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2235684-A None JP disclosed
EP-2603488-A1 DIFUNCTIONAL (METH)ACRYLATE WRITING MONOMERS Bayer Intellectual Property GmbH (DE) 2013-06-19 EP disclosed
US-20120059186-A1 RADIATION CURABLE COMPOSITIONS ALLNEX BELGIUM S.A. (BE) 2012-03-08 US disclosed
WO-2012020061-A1 DIFUNCTIONAL (METH)ACRYLATE WRITING MONOMERS BAYER MATERIALSCIENCE AG (DE) 2012-02-16 WO disclosed
EP-2267050-A1 Radiation Curable Compositions Cytec Surface Specialties, S.A. (BE) 2010-12-29 EP disclosed
JP-H02235684-A THERMALLY SENSITIVE RECORDING MEDIUM KAWASAKI KASEI CHEM LTD 1990-09-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059186-A1 RADIATION CURABLE COMPOSITIONS XRCC6, XRCC5, RAD51 LMNA 2146/4885KDM1A 1433/4885MAOA 902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.