Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577105 | 1.00 | KDM1A (0.33) | KDM1ATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL22105 | 0.89 | — | — | |
| SCHEMBL27650255 | 0.86 | — | — | |
| SCHEMBL9402771 | 0.85 | TSHR (0.36) | TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16738682 | 0.85 | — | — | |
| Methane SCHEMBL23927285 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL797498 | 0.85 | — | — | |
| SCHEMBL7851077 | 0.85 | — | — | |
| SCHEMBL3312437 | 0.85 | — | — | |
| SCHEMBL9285293 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11141357-B2 | Dental adhesive | DENTSPLY SIRONA INC. (US) | 2021-10-12 | — | — | US | disclosed |
| US-20210137795-A1 | DENTAL ADHESIVE | DENTSPLY SIRONA INC. (US) | 2021-05-13 | — | — | US | disclosed |
| US-20180214351-A1 | DENTAL ADHESIVE | DENTSPLY SIRONA INC. (US) | 2018-08-02 | — | — | US | disclosed |
| EP-2895138-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-11-22 | — | — | EP | disclosed |
| EP-2895138-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-11-22 | — | — | EP | disclosed |
| WO-2017017156-A1 | DENTAL ADHESIVE | DENTSPLY DETREY GMBH (DE) | 2017-02-02 | — | — | WO | disclosed |
| EP-2895138-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014040729-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2014-03-20 | — | — | WO | disclosed |
| WO-2014040729-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2014-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11141357-B2 | Dental adhesive | CDH1, ITGA5, ICAM1 | KDM1A 1861/4885TSHR 4642/4885ALDH1A1 404/4885 |
| US-20210137795-A1 | DENTAL ADHESIVE | CDH1, ITGA5, ICAM1 | KDM1A 1861/4885TSHR 4642/4885ALDH1A1 404/4885 |
| US-20180214351-A1 | DENTAL ADHESIVE | CDH1, ITGA5, ICAM1 | KDM1A 1861/4885TSHR 4642/4885ALDH1A1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.