Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | DHPS | P49366 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577515 | 0.91 | KMT2A (0.71) | KMT2AALDH1A1L3MBTL1MEN1NPSR1 | |
| SCHEMBL30786798 | 0.80 | ALDH1A1 (0.53) | KMT2AALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL2437490 | 0.80 | ALDH1A1 (0.53) | KMT2AALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL15614430 | 0.76 | KMT2A (1.00) | KMT2AALDH1A1L3MBTL1MEN1NPSR1 | |
| SCHEMBL23905108 | 0.72 | KMT2A (0.65) | KMT2AALDH1A1L3MBTL1MEN1NPSR1 | |
| SCHEMBL15577511 | 0.72 | KMT2A (0.65) | KMT2AALDH1A1L3MBTL1MEN1NPSR1 | |
| SCHEMBL10305008 | 0.70 | KMT2A (0.50) | KMT2AALDH1A1L3MBTL1MEN1NPSR1 | |
| SCHEMBL28312297 | 0.70 | KMT2A (0.61) | KMT2AALDH1A1L3MBTL1MEN1NPSR1 | |
| SCHEMBL31685827 | 0.69 | KMT2A (0.65) | KMT2AALDH1A1L3MBTL1MEN1NPSR1 | |
| SCHEMBL16684757 | 0.69 | CYP1A2 (0.50) | KMT2AMEN1LMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014043252-A2 | THERAPEUTIC HYDROXYPYRIDINONES, HYDROXYPYRIMIDINONES AND HYDROXYPYRIDAZINONES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-03-20 | — | — | WO | disclosed |