Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 6/20 | 0.50 |
| ▸ | NOS1 | P29475 | 6/20 | 0.50 |
| ▸ | NOS2 | P35228 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13198582 | 0.81 | — | — | |
| SCHEMBL13368176 | 0.66 | NOS3 (0.48) | NOS3NOS1NOS2KMT2A | |
| SCHEMBL14441515 | 0.66 | NOS3 (0.48) | NOS3NOS1NOS2KMT2A | |
| SCHEMBL16489783 | 0.66 | — | — | |
| SCHEMBL12422425 | 0.66 | NOS3 (0.48) | NOS3NOS1NOS2KMT2A | |
| SCHEMBL24971583 | 0.66 | NOS3 (0.48) | NOS3NOS1NOS2KMT2A | |
| SCHEMBL3432178 | 0.66 | — | — | |
| SCHEMBL10296536 | 0.66 | — | — | |
| SCHEMBL8329831 | 0.66 | NOS3 (0.48) | NOS3NOS1NOS2KMT2A | |
| SCHEMBL29282073 | 0.66 | NOS3 (0.48) | NOS3NOS1NOS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185570-B1 | NOVEL ACTIVATORS OF GLUCOKINASE | METABASIS THERAPEUTICS INC (US) | 2014-03-19 | — | — | EP | disclosed |