Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | PREP | P48147 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24350080 | 1.00 | CHRM2 (0.54) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL880528 | 0.88 | CHRM2 (0.56) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL21441814 | 0.88 | CHRM2 (0.56) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL26805930 | 0.88 | CHRM2 (0.56) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL12333780 | 0.88 | CHRM2 (0.56) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL11917924 | 0.88 | CHRM2 (0.50) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL2909390 | 0.81 | CHRM2 (0.53) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL14665083 | 0.80 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL11917929 | 0.80 | CHRM2 (0.53) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL11934300 | 0.79 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3207042-A1 | ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH AMINOALKOXY SUBSTITUTION | Idorsia Pharmaceuticals Ltd (CH) | 2017-08-23 | — | — | EP | disclosed |
| WO-2016059097-A1 | ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH AMINOALKOXY SUBSTITUTION | ACTELION PHARMACEUTICALS LTD (CH) | 2016-04-21 | — | — | WO | disclosed |
| EP-2094711-B1 | STRUCTURAL MIMETICS OF PROLINE-RICH PEPTIDES AND THE PHARMACEUTICAL USE THEREOF | FORSCHUNGSVERBUND BERLIN EV (DE) | 2014-03-19 | — | — | EP | disclosed |