SCHEMBL15580435

SCHEMBL15580435

CC(C)(C)c1cccc2c1O2

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.46
AHR P35869 3/20 0.40
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KIF11 P52732 1/20 0.34
ALOX12 P18054 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25491505 0.94 AHR (0.50) CA2AHRGABRA1GABRB2ALDH1A1
SCHEMBL25491225 0.82 AHR (0.39) CA2AHRGABRA1GABRB2ALDH1A1
SCHEMBL25490550 0.82 AHR (0.39) CA2AHRGABRA1GABRB2ALDH1A1
SCHEMBL13027814 0.77 ATM (0.43) CA2AHRGABRA1GABRB2ALDH1A1
SCHEMBL5474461 0.76 AHR (0.40) CA2AHR
SCHEMBL3101447 0.76 CA2 (0.34) CA2GABRA1GABRB2
SCHEMBL3103561 0.76 CA2 (0.34) CA2AHRGABRA1GABRB2
SCHEMBL811488 0.74 DRD1 (0.46) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL762016 0.74 ABCG2 (0.44) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL761139 0.74 ITGB2 (0.44) CA2ALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303150-A High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2020-06-19 CN claimed
CN-111303150-B High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2021-10-19 CN disclosed
CN-111303150-A High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2020-06-19 CN disclosed
EP-2521727-B1 NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE INVENTIVA (FR) 2014-03-19 EP disclosed