Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008702 | 0.83 | TSHR (0.54) | ALDH1A1SLC1A1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL7261708 | 0.81 | KMT2A (0.49) | ALDH1A1SLC1A1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL23673195 | 0.81 | KMT2A (0.49) | ALDH1A1SLC1A1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL24374486 | 0.80 | ALDH1A1 (0.47) | ALDH1A1SLC1A1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL7789021 | 0.80 | ALDH1A1 (0.55) | ALDH1A1SLC1A1CA1APOBEC3AAPOBEC3G | |
| SCHEMBL25980247 | 0.80 | ALDH1A1 (0.51) | ALDH1A1SLC1A1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL14408397 | 0.79 | ALDH1A1 (0.58) | ALDH1A1SLC1A1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL16673135 | 0.79 | ALDH1A1 (0.58) | ALDH1A1SLC1A1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL16673248 | 0.79 | MAPT (0.57) | ALDH1A1SLC1A1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL584760 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SLC1A1KMT2ASLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576534-B1 | 1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2014-03-19 | — | — | EP | disclosed |