Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10142790 | 0.87 | TMPRSS2 (0.30) | TMPRSS2 | |
| SCHEMBL18636437 | 0.84 | TMPRSS2 (0.43) | TMPRSS2 | |
| SCHEMBL15580657 | 0.83 | CYP3A4 (0.34) | — | |
| SCHEMBL10142742 | 0.83 | CYP3A4 (0.34) | — | |
| SCHEMBL20878404 | 0.83 | TMPRSS2 (0.32) | TMPRSS2 | |
| SCHEMBL14845670 | 0.82 | — | — | |
| SCHEMBL10174704 | 0.82 | RIPK1 (0.32) | — | |
| SCHEMBL29461488 | 0.81 | TMPRSS2 (0.38) | TMPRSS2 | |
| SCHEMBL18636611 | 0.81 | TMPRSS2 (0.34) | TMPRSS2 | |
| SCHEMBL10142368 | 0.81 | TMPRSS2 (0.31) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576534-B1 | 1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2014-03-19 | — | — | EP | disclosed |