Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456120 | 0.91 | IGF1R (1.00) | IGF1R | |
| SCHEMBL4461050 | 0.87 | IGF1R (1.00) | IGF1R | |
| SCHEMBL12653098 | 0.79 | IGF1R (0.82) | IGF1R | |
| SCHEMBL4457637 | 0.79 | IGF1R (1.00) | IGF1R | |
| SCHEMBL4455738 | 0.77 | IGF1R (1.00) | IGF1R | |
| SCHEMBL14025723 | 0.77 | IGF1R (1.00) | IGF1R | |
| SCHEMBL11341966 | 0.76 | IGF1R (1.00) | IGF1R | |
| SCHEMBL4463246 | 0.75 | IGF1R (0.77) | IGF1R | |
| SCHEMBL14050435 | 0.74 | IGF1R (0.84) | IGF1R | |
| SCHEMBL4459218 | 0.73 | IGF1R (0.85) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139484-B9 | METHODS OF TREATING CANCER USING PYRIDOPYRIMIDINONE INHIBITORS OF PI3K ALPHA | EXELIXIS INC (US) | 2014-06-11 | — | — | EP | disclosed |