Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568063 | 0.84 | KMT2A (0.57) | KMT2APOLBALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL15599447 | 0.82 | TAAR1 (0.53) | KMT2APOLBTAAR1HTR6 | |
| SCHEMBL16971182 | 0.82 | TAAR1 (0.53) | KMT2AHRH3ALDH1A1TAAR1 | |
| SCHEMBL26810022 | 0.82 | RECQL (0.42) | KMT2AHRH3POLBALDH1A1KEAP1 | |
| SCHEMBL27033424 | 0.77 | KCNH2 (0.46) | KMT2APOLBALDH1A1 | |
| SCHEMBL16980137 | 0.73 | TAAR1 (0.47) | KMT2AALDH1A1TAAR1HTR6CYP2C19 | |
| SCHEMBL15599406 | 0.73 | TAAR1 (0.58) | KMT2AALDH1A1TAAR1HTR6 | |
| SCHEMBL3982535 | 0.68 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL18609544 | 0.66 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL12849816 | 0.66 | KMT2A (0.44) | KMT2APOLBALDH1A1GLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014023934-A1 | IMMUNOMODULATORY COMPOUNDS | UNIVERSITY OF STRATHCLYDE (GB) | 2014-02-13 | — | — | WO | disclosed |