Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1559842 | 0.89 | CYP3A4 (0.41) | CYP3A4TDP1GAA | |
| SCHEMBL1559552 | 0.89 | CYP3A4 (0.41) | CYP3A4TDP1ESR1ESR2OPRM1 | |
| SCHEMBL1559812 | 0.87 | CYP3A4 (0.39) | CYP3A4TDP1OPRM1 | |
| SCHEMBL7922206 | 0.78 | CYP3A4 (0.36) | CYP3A4TDP1 | |
| SCHEMBL15657900 | 0.78 | HDAC4 (0.36) | CYP3A4TDP1OPRM1 | |
| SCHEMBL15660290 | 0.76 | CYP3A4 (0.35) | CYP3A4TDP1OPRM1 | |
| SCHEMBL5694566 | 0.74 | HTR2A (0.48) | CYP3A4TDP1OPRM1CYP2D6MEN1 | |
| SCHEMBL15658981 | 0.72 | CYP3A4 (0.41) | CYP3A4TDP1GAA | |
| SCHEMBL7060523 | 0.69 | CYP3A4 (0.38) | CYP3A4TDP1GAA | |
| Benzene SCHEMBL6890099 | 0.63 | TDP1 (1.00) | CYP3A4TDP1ESR1ESR2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2700630-B1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2018-03-21 | — | — | EP | disclosed |
| CN-105218378-A | Prepare the method for substituted biphenyl | BASF SE | 2016-01-06 | — | — | CN | disclosed |
| EP-2303828-B1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2014-07-30 | — | — | EP | disclosed |
| EP-2700630-A2 | Method for producing substituted biphenyls | BASF SE (DE) | 2014-02-26 | — | — | EP | disclosed |
| EP-2303828-A2 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009156359-A2 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2009-12-30 | — | — | WO | disclosed |