Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15599620 | 0.94 | REN (0.61) | REN | |
| SCHEMBL17012988 | 0.94 | REN (0.64) | REN | |
| SCHEMBL17012998 | 0.94 | REN (0.60) | REN | |
| SCHEMBL15599740 | 0.93 | REN (0.59) | REN | |
| SCHEMBL15599792 | 0.86 | REN (0.59) | REN | |
| SCHEMBL17188951 | 0.85 | REN (0.59) | REN | |
| SCHEMBL17012991 | 0.85 | REN (0.63) | REN | |
| SCHEMBL17012989 | 0.85 | REN (0.62) | REN | |
| SCHEMBL17012970 | 0.84 | REN (0.70) | REN | |
| SCHEMBL17012993 | 0.84 | REN (0.61) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2933248-A1 | NOVEL RENIN INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014042263-A1 | NOVEL RENIN INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2014-03-20 | — | — | WO | disclosed |