Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.43 |
| ▸ | CNR2 | P34972 | 10/20 | 0.38 |
| ▸ | CNR1 | P21554 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17013295 | 0.87 | HPGD (0.36) | CNR2 | |
| SCHEMBL19826792 | 0.80 | TLR8 (0.44) | TLR8CNR2CNR1TSHR | |
| SCHEMBL649215 | 0.71 | TSHR (0.47) | TLR8CNR2TSHR | |
| SCHEMBL17013306 | 0.71 | GAA (0.37) | CNR2CNR1 | |
| SCHEMBL651866 | 0.70 | TLR8 (0.66) | TLR8TSHR | |
| SCHEMBL19826534 | 0.70 | SIGMAR1 (0.36) | TLR8 | |
| SCHEMBL5298716 | 0.69 | TLR8 (0.60) | TLR8TSHR | |
| SCHEMBL5290885 | 0.69 | TLR8 (0.60) | TLR8TSHR | |
| SCHEMBL5811655 | 0.69 | TLR8 (0.60) | TLR8TSHR | |
| SCHEMBL5293056 | 0.69 | TLR8 (0.60) | TLR8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014042263-A1 | NOVEL RENIN INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2014-03-20 | — | — | WO | disclosed |