Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.84 |
| ▸ | NPC1 | O15118 | 3/20 | 0.84 |
| ▸ | RAB9A | P51151 | 3/20 | 0.84 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.84 |
| ▸ | KCNK3 | O14649 | 14/20 | 0.77 |
| ▸ | KCNK9 | Q9NPC2 | 10/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20848006 | 0.94 | NPC1 (0.78) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL15599961 | 0.88 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL4253897 | 0.85 | KCNK3 (0.93) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL259666 | 0.83 | KCNK3 (0.87) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL30608967 | 0.83 | KCNK3 (0.87) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL16675166 | 0.83 | KCNK3 (0.89) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL13220719 | 0.83 | MEN1 (0.68) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL7325287 | 0.82 | KMT2A (0.78) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL19491385 | 0.82 | KCNK3 (0.85) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL12447826 | 0.82 | NPC1 (0.82) | MEN1KMT2ANPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150238466-A1 | LIM KINASE INHIBITORS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2015-08-27 | — | — | US | disclosed |
| US-20150238466-A1 | LIM KINASE INHIBITORS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2015-08-27 | — | — | US | disclosed |
| WO-2014002101-A1 | LIM KINASE INHIBITORS | RAMOT AT TEL-AVIV UNIVERSITY LTD (IL) | 2014-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238466-A1 | LIM KINASE INHIBITORS | LIMK1, LIMK2, LIMA1 | MEN1 1780/4885KMT2A 2529/4885NPC1 4081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.