Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.78 |
| ▸ | RAB9A | P51151 | 8/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.78 |
| ▸ | MEN1 | O00255 | 6/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.67 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15599962 | 0.94 | MEN1 (0.84) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL13220719 | 0.88 | MEN1 (0.68) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL15599961 | 0.84 | MEN1 (0.78) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL12447826 | 0.84 | NPC1 (0.82) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL2467402 | 0.84 | PLAU (0.78) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL4253897 | 0.84 | KCNK3 (0.93) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL7335241 | 0.84 | PLAU (0.62) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL29068810 | 0.83 | DEGS1 (0.72) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL22629672 | 0.82 | NPC1 (0.70) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL8085694 | 0.82 | NPC1 (0.80) | NPC1RAB9AKMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190092720-A1 | FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | BARUCH S BLUMBERG INST (US) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092720-A1 | FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | HAVCR2, PHB2, PHB1 | NPC1 539/4885RAB9A 3534/4885KMT2A 2493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.