Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560103 | 1.00 | BACE1 (0.34) | BACE1SMYD2 | |
| SCHEMBL12621025 | 1.00 | BACE1 (0.34) | BACE1SMYD2 | |
| SCHEMBL1559040 | 0.94 | BACE1 (0.33) | BACE1SMYD2 | |
| SCHEMBL1559042 | 0.94 | BACE1 (0.33) | BACE1SMYD2 | |
| SCHEMBL1806564 | 0.91 | BACE1 (0.34) | BACE1SMYD2 | |
| SCHEMBL1806566 | 0.91 | BACE1 (0.34) | BACE1SMYD2 | |
| SCHEMBL1139569 | 0.88 | BACE1 (0.35) | BACE1SMYD2 | |
| SCHEMBL1139938 | 0.88 | BACE1 (0.35) | BACE1SMYD2 | |
| SCHEMBL15818185 | 0.88 | BACE1 (0.35) | BACE1SMYD2 | |
| SCHEMBL1139565 | 0.88 | BACE1 (0.35) | BACE1SMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501961-B2 | HIV protease inhibitors and methods for using | PURDUE RESEARCH FOUNDATION (US) | 2013-08-06 | — | — | US | disclosed |
| US-20110118330-A1 | HIV PROTEASE INHIBITORS AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2011-05-19 | — | — | US | disclosed |
| EP-2304043-A1 | HIV PROTEASE INHIBITORS AND METHODS FOR USING | Purdue Research Foundation (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010006050-A1 | HIV PROTEASE INHIBITORS AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118330-A1 | HIV PROTEASE INHIBITORS AND METHODS FOR USING | SERPINB1, PREP, PEPD | BACE1 69/4885SMYD2 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.