Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15601041 | 0.77 | MEN1 (0.49) | CYP2C9MEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL9486483 | 0.75 | AKR1C1 (0.43) | MEN1CYP2D6KMT2AADRB2HDAC4 | |
| SCHEMBL3830478 | 0.72 | HDAC4 (0.39) | CYP2C9MEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL1662269 | 0.70 | HDAC4 (0.44) | CYP2C9CYP2D6TSHRCYP3A4CYP1A2 | |
| SCHEMBL2896976 | 0.69 | CYP2C9 (0.55) | CYP2C9MEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL11733722 | 0.69 | CYP2C9 (0.55) | CYP2C9MEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL390594 | 0.69 | CYP2C9 (0.55) | CYP2C9MEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL3834022 | 0.68 | SLC6A4 (0.44) | BRD4LMNATSHRCYP3A4ADRB2 | |
| Hydrochloric Acid SCHEMBL29398375 | 0.67 | CYP2C9 (0.53) | CYP2C9MEN1CYP2D6CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL28524755 | 0.67 | CYP2C9 (0.53) | CYP2C9MEN1CYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447038-B2 | Substituted B-amino acid derivatives as CXCR3 receptor antagonists | SANOFI (FR) | 2016-09-20 | — | — | US | disclosed |
| US-9447038-B2 | Substituted B-amino acid derivatives as CXCR3 receptor antagonists | SANOFI (FR) | 2016-09-20 | — | — | US | disclosed |
| EP-2852578-B1 | SUBSTITUTED ß-AMINO ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS | SANOFI SA (FR) | 2016-04-27 | — | — | EP | disclosed |
| US-20150073004-A1 | SUBSTITUTED B-AMINO ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS | SANOFI (FR) | 2015-03-12 | — | — | US | disclosed |
| US-20150073004-A1 | SUBSTITUTED B-AMINO ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS | SANOFI (FR) | 2015-03-12 | — | — | US | disclosed |
| WO-2013174485-A1 | SUBSTITUTED ß-AMINO ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS | SANOFI (FR) | 2013-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073004-A1 | SUBSTITUTED B-AMINO ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS | CXCR3, CXCR1, CXCR2 | CYP2C9 3446/4885MEN1 4459/4885CYP2D6 2841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.