Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | BCR | P11274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560182 | 0.89 | NPC1 (0.41) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL1560195 | 0.88 | MAPT (0.45) | ABL1ABCB1BCRADORA1ADORA2A | |
| SCHEMBL1938749 | 0.81 | ADORA2A (0.46) | ADORA1ADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1559578 | 0.80 | CYP1A1 (0.35) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL1560637 | 0.79 | CTSA (0.36) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1558934 | 0.78 | NPC1 (0.41) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL1559520 | 0.78 | CTSA (0.35) | MAPTMEN1KMT2AKDM4ECYP1A1 | |
| SCHEMBL1560628 | 0.77 | ERN1 (0.37) | ALDH1A1MAPTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1560532 | 0.77 | CTSA (0.34) | MAPTCYP1A1CYP1A2CYP1B1BACE1 | |
| SCHEMBL1937703 | 0.76 | ADORA2A (0.48) | ABL1ABCB1BCRADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092544-A1 | FUNGICIDAL PYRIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-04-21 | — | — | US | claimed |
| EP-2303843-A2 | FUNGICIDAL PYRIDINES | E. I. du Pont de Nemours and Company (US) | 2011-04-06 | — | — | EP | claimed |
| WO-2009158257-A2 | FUNGICIDAL PYRIDINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | claimed |
| US-20110092544-A1 | FUNGICIDAL PYRIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-04-21 | — | — | US | disclosed |
| EP-2303843-A2 | FUNGICIDAL PYRIDINES | E. I. du Pont de Nemours and Company (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009158257-A2 | FUNGICIDAL PYRIDINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092544-A1 | FUNGICIDAL PYRIDINES | CBR3, CBR1, CYP8B1 | ABL1 616/4885ABCB1 613/4885BCR 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.