Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 15/20 | 0.54 |
| ▸ | CA2 | P00918 | 15/20 | 0.54 |
| ▸ | CA9 | Q16790 | 15/20 | 0.54 |
| ▸ | CA12 | O43570 | 12/20 | 0.54 |
| ▸ | FYN | P06241 | 5/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1943789 | 0.89 | CA2 (0.69) | CA1CA2CA9CA12FYN | |
| SCHEMBL1944265 | 0.87 | CA1 (0.55) | CA1CA2CA9CA12FYN | |
| SCHEMBL1946905 | 0.85 | CA1 (0.55) | CA1CA2CA9CA12FYN | |
| SCHEMBL1945596 | 0.84 | CA12 (0.54) | CA1CA2CA9CA12FYN | |
| SCHEMBL1944821 | 0.84 | FYN (0.48) | FYN | |
| SCHEMBL1946953 | 0.83 | CA1 (0.55) | CA1CA2CA9CA12FYN | |
| SCHEMBL1946745 | 0.83 | FYN (0.69) | CA1CA2CA9CA12FYN | |
| SCHEMBL1944066 | 0.83 | FYN (0.72) | CA1CA2CA9CA12FYN | |
| SCHEMBL1946803 | 0.83 | FYN (0.68) | CA1CA2CA9CA12FYN | |
| SCHEMBL1649750 | 0.82 | FYN (0.60) | CA1CA2CA9CA12FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307425-B1 | IMIDAZOTHIADIAZOLES DERIVATIVES | MERCK PATENT GMBH (DE) | 2014-03-26 | — | — | EP | claimed |
| EP-2307425-B1 | IMIDAZOTHIADIAZOLES DERIVATIVES | MERCK PATENT GMBH (DE) | 2014-03-26 | — | — | EP | disclosed |