Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.32 |
| ▸ | PRF1 | P14222 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.31 |
| ▸ | IL2 | P60568 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12129775 | 0.90 | PGR (0.37) | HDAC1HDAC2PGRHDAC3PRF1 | |
| SCHEMBL12129785 | 0.84 | PGR (0.37) | PGR | |
| SCHEMBL12129768 | 0.82 | PTPRC (0.36) | HDAC1 | |
| SCHEMBL12129779 | 0.80 | IL2 (0.33) | IL2 | |
| SCHEMBL12129782 | 0.80 | IL2 (0.36) | IL2 | |
| SCHEMBL12129766 | 0.80 | BRD4 (0.40) | PGR | |
| SCHEMBL12129789 | 0.80 | NR4A2 (0.36) | HDAC1HDAC2 | |
| SCHEMBL12129783 | 0.80 | GSK3B (0.38) | — | |
| SCHEMBL12129771 | 0.78 | IL2 (0.35) | IL2 | |
| SCHEMBL12129786 | 0.78 | AGPAT2 (0.39) | IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680012-B2 | 4-phenyl-pyrane-3,5-diones,4-phenyl-thiopyrane-3,6-diones and cyclohexanetriones as novel herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2014-03-25 | — | — | US | disclosed |